An Efficient Synthesis of 4-Aryl-1,4-dihydropyridines Via VB1 Catalyzed Hantzsch Reaction

Author(s): Chuangang Fan, Mingzhi Song

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 10 , 2011

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An environmentally rapid and benign protocol for the synthesis of 4-aryl-1,4-dihydropyridines compounds using VB1 as a catalyst under microwave irradiation and solvent-free conditions has been achieved. The procedure is operationally simple, giving good to high product yield.

Keywords: 4-Aryl-1, 4-dihydropyridines, VB1, antitumor, antimutagenic, geroprotective, antidiabetic agents, bioactivity, antiaggregatory, aromatic aldehydes

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Article Details

Year: 2011
Published on: 01 March, 2012
Page: [707 - 711]
Pages: 5
DOI: 10.2174/157017811799304133
Price: $65

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