Abstract
Lung cancer comprises of two major clinically relevant types, non-small cell lung cancer (NSCLC) representing about 85% of all cases and small cell lung cancer (SCLC) accounting for the remaining 15%. Despite recent advancements that include new understanding of the molecular mechanisms involved in cancer pathogenesis and introduction of new treatments, lung cancer continues to reign as the leading cause of cancer deaths worldwide. Innovations in genomics-based technologies are becoming rapidly integrated into lung cancer research and the results of these efforts have started to yield tangible advances in improved understanding and treatment of lung cancer.
Keywords: Lung cancer, oncogene, cancer stem cell, stroma, cancer-associated fibroblasts, genomics, biomarkers, personalized medicine, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC)
Current Respiratory Medicine Reviews
Title: Genomic and Cellular Pathology of Lung Cancer
Volume: 7 Issue: 5
Author(s): Sandy D. Der, Roya Navab, Kota Ishizawa and Ming-Sound Tsao
Affiliation:
Keywords: Lung cancer, oncogene, cancer stem cell, stroma, cancer-associated fibroblasts, genomics, biomarkers, personalized medicine, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC)
Abstract: Lung cancer comprises of two major clinically relevant types, non-small cell lung cancer (NSCLC) representing about 85% of all cases and small cell lung cancer (SCLC) accounting for the remaining 15%. Despite recent advancements that include new understanding of the molecular mechanisms involved in cancer pathogenesis and introduction of new treatments, lung cancer continues to reign as the leading cause of cancer deaths worldwide. Innovations in genomics-based technologies are becoming rapidly integrated into lung cancer research and the results of these efforts have started to yield tangible advances in improved understanding and treatment of lung cancer.
Export Options
About this article
Cite this article as:
D. Der Sandy, Navab Roya, Ishizawa Kota and Tsao Ming-Sound, Genomic and Cellular Pathology of Lung Cancer, Current Respiratory Medicine Reviews 2011; 7 (5) . https://dx.doi.org/10.2174/157339811797189740
DOI https://dx.doi.org/10.2174/157339811797189740 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Anticancer Cytotoxic Agents
Current Medicinal Chemistry - Anti-Cancer Agents Simultaneous Determination of Cytochrome P450 Oxidation Capacity in Humans: A Review on the Phenotyping Cocktail Approach
Current Pharmaceutical Biotechnology Interferon Treatment in Patients with Hypereosinophilia
Current Drug Targets Functional Foods: Salient Features and Clinical Applications
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Fusogenic Oncolytic Herpes Simplex Viruses as a Potent and Personalized Cancer Vaccine
Current Pharmaceutical Biotechnology microRNAs, Gap Junctional Intercellular Communication and Mesenchymal Stem Cells in Breast Cancer Metastasis
Current Cancer Therapy Reviews A Review on the Synthesis and Anti-cancer Activity of 2-substituted Quinolines
Anti-Cancer Agents in Medicinal Chemistry Contrast Agents in X-Ray Computed Tomography and Its Applications in Oncology
Anti-Cancer Agents in Medicinal Chemistry The HOX Genes Network in Uro-Genital Cancers: Mechanisms and Potential Therapeutic Implications
Current Medicinal Chemistry Genetically Modified Dendritic Cells for Cancer Immunotherapy
Current Gene Therapy Role of Rap2 and its Downstream Effectors in Tumorigenesis
Anti-Cancer Agents in Medicinal Chemistry Molecular Mechanisms of Anti-cancer Action of Garlic Compounds in Neuroblastoma
Anti-Cancer Agents in Medicinal Chemistry The Emerging Role of Vascular Endothelial Growth Factor (VEGF) in Vascular Homeostasis: Lessons from Recent Trials with Anti-VEGF Drugs
Current Vascular Pharmacology Research Advances on Biological Activities of Tanshinone IIA- A Mini Review
Mini-Reviews in Organic Chemistry FoxQ1 is a Novel Molecular Target for Pancreatic Cancer and is Associated with Poor Prognosis
Current Molecular Medicine Targeting the Phosphatidylinositol 3-Kinase/AKT Pathway for the Treatment of Multiple Myeloma
Current Medicinal Chemistry Nanobiotechnology: An Efficient Approach to Drug Delivery of Unstable Biomolecules
Current Protein & Peptide Science Non-Transferrin Bound Iron - Determination in Biological Material and Clinical Implications
Current Pharmaceutical Analysis Multi-target Pharmacological Effects of Platycodin D
Mini-Reviews in Organic Chemistry Molecular Modeling, Docking, Dynamics and Simulation of Gefitinib and its Derivatives with EGFR in Non-small Cell Lung Cancer
Current Computer-Aided Drug Design