PlantPIs – An Interactive Web Resource on Plant Protease Inhibitors

Author(s): Arianna Consiglio, Giorgio Grillo, Flavio Licciulli, Luigi R. Ceci, Sabino Liuni, Nicola Losito, Mariateresa Volpicella, Raffaele Gallerani, Francesca De Leo

Journal Name: Current Protein & Peptide Science

Volume 12 , Issue 5 , 2011


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Abstract:

PlantPIs is a web querying system for a database collection of plant protease inhibitors data. Protease inhibitors in plants are naturally occurring proteins that inhibit the function of endogenous and exogenous proteases. In this paper the design and development of a web framework providing a clear and very flexible way of querying plant protease inhibitors data is reported. The web resource is based on a relational database, containing data of plants protease inhibitors publicly accessible, and a graphical user interface providing all the necessary browsing tools, including a data exporting function. PlantPIs contains information extracted principally from MEROPS database, filtered, annotated and compared with data stored in other protein and gene public databases, using both automated techniques and domain expert evaluations. The data are organized to allow a flexible and easy way to access stored information. The database is accessible at http://www.plantpis.ba.itb.cnr.it/.

Keywords: Bioinformatics, database, Kingdom plantae, MEROPS, protease inhibitors, web querying system, anti-metabolic proteins, sequence homology, pseudo-substrates, syntactic control, Universal Protein Resource, hierarchical, NCBI, Domains, Taxonomies, ETL process

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Article Details

VOLUME: 12
ISSUE: 5
Year: 2011
Page: [448 - 454]
Pages: 7
DOI: 10.2174/138920311796391052
Price: $65

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