Title: Caffeic Acid, A Versatile Pharmacophore: An Overview
VOLUME: 11 ISSUE: 8
Author(s):M. Touaibia, J. Jean-Francois and J. Doiron
Affiliation:Department of Chemistry and Biochemistry, Universite de Moncton, Moncton, NB, E1A 3E9, Canada.
Keywords:Caffeic acid, anticancer, antioxidant, anti-inflammatory, integrase inhibitors, structure-activity relationships, Pharmacophore, scaffold, natural products, antiviral, synthetic caffeic acid
Abstract: The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.
