Title: Synthesis and Biological Properties of Dihydro-Oxadiazine-Based Heterocyclic Derivatives
VOLUME: 11 ISSUE: 8
Author(s):S. Ke, X. Cao, Y. Liang, K. Wang and Z. Yang
Affiliation:Laboratory of Green Chemistry and Synthesis, Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Keywords:Dihydro-oxadiazine, heterocycle, synthesis, biological activity, heterocyclic scaffold, cardiovascular, antitumor, antibacterial, antimicrobial, acricidal, insecticidal, plant-growth regulating, chitin biosynthesis, monoamine oxidase
Abstract: Dihydro-oxadiazine and its derivatives have been demonstrated to be important heterocyclic scaffold platform with bioactive diversity, which present wide activities such as cardiovascular, antitumor, antibacterial, antimicrobial, acricidal, insecticidal, plant-growth regulating, chitin biosynthesis inhibitors and monoamine oxidase inhibition. Versatile features of dihydro-oxadiazine heterocycles have emerged, so the aim of the present paper was to review the recent advances of dihydro-oxadiazine-based heterocyclic derivatives mainly including synthesis and biological activities.