Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging

Author(s): Donald D. Nolting, John C. Gore, Wellington Pham

Journal Name: Current Organic Synthesis

Volume 8 , Issue 4 , 2011

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Abstract:

The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.

Keywords: Cyanine, fluorescence, FRET, imaging, optical, probe, rhodamine, near-infrared (NIR) region, near-infrared (NIR) dyes, Fluorescent Dyes, Cyanine Dyes

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Article Details

VOLUME: 8
ISSUE: 4
Year: 2011
Page: [521 - 534]
Pages: 14
DOI: 10.2174/157017911796117223
Price: $65

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