Abstract
An efficient and convenient approach towards the synthesis of series of tetrahydro-4H-chromenes via one pot three component coupling reactions of aldehyde, dimedone and malononitrile carried out at room temperature in presence of triethylammonium acetate [TEAA] ionic liquid as a catalyst. Reusability of the catalyst with optimized reaction conditions has also been investigated. The present methodology was found to be economically feasible and environmentally benign.
Keywords: Triethylammonium acetate (TEAA), tetrahydro-4H-chromenes, room temperature, malononitrile, Beckmann rearrangement, Polyhydroquinoline, Esterification, aldol reactions, Reaction, Transesterification
Letters in Organic Chemistry
Title: Triethylammonium Acetate [TEAA]: An Efficient Catalyst for One Pot Synthesis of Tetrahydro-4H-chromene Derivatives
Volume: 8 Issue: 4
Author(s): Ravi Balaskar, Sandip Gavade, Madhav Mane, Pramod Pabrekar, Murlidhar Shingare and Dhananjay Mane
Affiliation:
Keywords: Triethylammonium acetate (TEAA), tetrahydro-4H-chromenes, room temperature, malononitrile, Beckmann rearrangement, Polyhydroquinoline, Esterification, aldol reactions, Reaction, Transesterification
Abstract: An efficient and convenient approach towards the synthesis of series of tetrahydro-4H-chromenes via one pot three component coupling reactions of aldehyde, dimedone and malononitrile carried out at room temperature in presence of triethylammonium acetate [TEAA] ionic liquid as a catalyst. Reusability of the catalyst with optimized reaction conditions has also been investigated. The present methodology was found to be economically feasible and environmentally benign.
Export Options
About this article
Cite this article as:
Balaskar Ravi, Gavade Sandip, Mane Madhav, Pabrekar Pramod, Shingare Murlidhar and Mane Dhananjay, Triethylammonium Acetate [TEAA]: An Efficient Catalyst for One Pot Synthesis of Tetrahydro-4H-chromene Derivatives, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371430
DOI https://dx.doi.org/10.2174/157017811795371430 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Mechanisms of Acupuncture Effect on Alzheimer’s Disease in Animal- Based Researches
Current Topics in Medicinal Chemistry Amyotrophic Lateral Sclerosis: From Research to Therapeutic Attempts and Therapeutic Perspectives
Current Medicinal Chemistry Change in Body Mass Index Before and After Alzheimer’s Disease Onset
Current Alzheimer Research Benefits of Resistance Training in Older Adults
Current Aging Science Impaired DNA Damage Repair as a Common Feature of Neurodegenerative Diseases and Psychiatric Disorders
Current Molecular Medicine Topical Discoveries on Multi-Target Approach to Manage Alzheimer’s Disease
Current Drug Metabolism Neurotrophic Factors in the Pathogenesis of Neurological Disorders with Mental Retardation in Children
Current Pediatric Reviews Selective Elevation of Circulating CCL2/MCP1 Levels in Patients with Longstanding Post-vaccinal Macrophagic Myofasciitis and ASIA
Current Medicinal Chemistry Novel Anti-Inflammatory and Neuroprotective Agents for Parkinsons Disease
CNS & Neurological Disorders - Drug Targets Modulation of Apoptosis in Acute Ischemic Stroke as Treatment Challenges
Current Immunology Reviews (Discontinued) The Surgical Management of Parkinson's Disease
CNS & Neurological Disorders - Drug Targets Effects of Cholinergic Enhancing Drugs on Cholinergic Transporters in the Brain and Peripheral Blood Lymphocytes of Spontaneously Hypertensive Rats
Current Alzheimer Research Virgin Olive Oil and Hypertension
Current Vascular Pharmacology The Role of Blood-Brain Barrier Studies in the Pharmaceutical Industry
Current Drug Metabolism Dyslipidemia and Cardiovascular Disease Prevention in South Asians: A Review and Discussion of Causes, Challenges and Management Strategies
Current Diabetes Reviews Conference Report: 10th Clinical Trials on Alzheimer's Disease (CTAD), Boston MA, USA, November 1-4, 2017
CNS & Neurological Disorders - Drug Targets Pharmacogenetics of the Antiplatelet Effect of Aspirin
Current Pharmaceutical Design Therapeutic Potential of γ -Secretase Inhibitors and Modulators
Current Topics in Medicinal Chemistry Ultrasound Diagnostic Method in Vascular Dementia: Current Concepts
Current Medical Imaging The HIV Pandemic: A Forgotten Crisis?
Current Drug Targets - Infectious Disorders