Herpes Simplex Virus-Induced Ocular Diseases: Detrimental Interaction Between Virus and Host

Author(s): Georges M.G.M. Verjans, Arnd Heiligenhaus

Journal Name: Current Immunology Reviews (Discontinued)

Volume 7 , Issue 3 , 2011


Herpes simplex virus type 1 (HSV-1) is a common cause of ocular diseases, affecting all parts of the visual axis. HSV-1 keratitis and uveitis represent two prevalent ocular diseases. The outcome of these potentially sightthreatening conditions depends on prompt diagnosis and treatment in order to counteract the detrimental intra-ocular virus-host interaction. This review recapitulates current insights on the diagnosis, pathogenesis, and treatment of HSV-1 keratitis and uveitis in patients and in the respective mouse models.

Keywords: Herpes simplex virus, keratitis, uveitis, epidemiology, clinical symptoms, diagnosis, pathogenesis, treatment, Ocular Diseases, Neurotrophic keratitis, dendritic HSV lesion, Corneal endotheliitis, Stromal keratitis, Acute retinal necrosis

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Article Details

Year: 2011
Page: [310 - 327]
Pages: 18
DOI: 10.2174/157339511796196557
Price: $65

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