Peptide Array-Based Peptide-Cell Interaction Analysis

Author(s): Ryuji Kato, Chiaki Kaga, Kei Kanie, Mitoshi Kunimatsu, Mina Okochi, Hiroyuki Honda

Journal Name: Mini-Reviews in Organic Chemistry

Volume 8 , Issue 2 , 2011

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Abstract:

Peptide arrays represent a powerful research tool, especially for the development of medical applications to screen peptides for the replacement of animal-derived proteins. This minireview focuses on the applicability of cellulose-bound peptide arrays to assay peptide- cell interactions. Moreover, the successful combination of peptide array and bioinformatics to overcome the limitation of library size in array-type screenings is reviewed.

Keywords: Cell assay, cell adhesion, cell proliferation, cell specificity, bioinformatics, Peptide array, animal-derived proteins, cellulose-bound peptide arrays

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Article Details

VOLUME: 8
ISSUE: 2
Year: 2011
Page: [171 - 177]
Pages: 7
DOI: 10.2174/157019311795177790
Price: $65

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