A Facile and Efficient Approach to the Synthesis of Novel Chiral Molecular Tweezers Based on Deoxycholic Acid under Microwave Irradiation

Title: A Facile and Efficient Approach to the Synthesis of Novel Chiral Molecular Tweezers Based on Deoxycholic Acid under Microwave Irradiation

Volume: 8 Issue: 3

Author(s): Yu Chen, Zhi-Gang Zhao, Xing-Li Liu and Zhi-Chuan Shi

Affiliation:

Keywords: Molecular tweezer, deoxycholic acid, synthesis, microwave irradiation, molecular recognition

Abstract: A rapid, safe and efficient method for the synthesis of novel molecular tweezers with one chiral arm based on deoxycholic acid was reported. Ten new molecular tweezers have been synthesized in good yields. The structures of these new molecular tweezers were characterized by 1H NMR, IR, MS spectra and elemental analysis. These chiral molecular tweezers showed good enantioselectivity for D-amino acid methyl esters.

Cite this article as:

Chen Yu, Zhao Zhi-Gang, Liu Xing-Li and Shi Zhi-Chuan, A Facile and Efficient Approach to the Synthesis of Novel Chiral Molecular Tweezers Based on Deoxycholic Acid under Microwave Irradiation, Letters in Organic Chemistry 2011; 8 (3) . https://dx.doi.org/10.2174/157017811795038421