Vitamin D and Cardiovascular Disease: A Novel Agent for Reducing Cardiovascular Risk?

Author(s): Panagiotis Anagnostis, Vasilios G. Athyros, Fotini Adamidou, Matilda Florentin, Asterios Karagiannis

Journal Name: Current Vascular Pharmacology

Volume 8 , Issue 5 , 2010

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Vitamin D deficiency is a well-established risk factor for bone disease. Emerging data suggest a pleiotropic role of this agent in a variety of functions in humans. Epidemiological studies indicate an inverse association between vitamin D deficiency and the prevalence of cardiovascular disease (CVD), as well as individual cardiometabolic risk factors, such as hypertension, diabetes, dyslipidemia and the metabolic syndrome. Moreover, vitamin D deficiency has been implicated in the atherosclerotic process.

This review considers current data regarding the role of vitamin D deficiency in the development of CVD and addresses the effect of supplementation on cardiovascular outcomes.

Keywords: Vitamin D, cardiovascular disease, hypertension, diabetes mellitus, metabolic syndrome

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Article Details

Year: 2010
Page: [720 - 730]
Pages: 11
DOI: 10.2174/157016110792006978
Price: $65

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PDF: 27