Anesthesia and Postoperative Cognitive Dysfunction (POCD)

Author(s): Bettina Jungwirth, Walter Zieglgansberger, Eberhard Kochs, Gerhard Rammes

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 14 , 2009

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POCD describes a decline in cognitive function after surgery with a predominance in the elderly patient. Although there is general agreement that POCD is likely to be multifactorial, it remains unclear whether its occurrence is a result of the effects of surgery or general anesthesia. This review provides a synopsis of the available clinical and preclinical data and summarizes recent research relevant to the occurrence of POCD and possible pharmacologic algorithms for its prevention and treatment.

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Article Details

Year: 2009
Page: [1568 - 1579]
Pages: 12
DOI: 10.2174/138955709791012229
Price: $65

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