Abstract
A protein domain interaction prediction program was complied using C++ to predict whether a query protein could interact with other hub proteins. It is indicated that the proteins interacting with AATF (Apoptosis-Antagonizing Transcription Factor) possess a common conservative pattern: I-x(0,1)-E-x(2)-[A/E/N/T]-x-[E/K]. Our method is attempted to integrate the characteristics of protein interaction network with the simplest building blocks-conservative patterns.
Keywords: AD associated protein interaction network, signal pathway, conservative interaction pattern
Protein & Peptide Letters
Title: A Novel Approach to Predict Protein-Protein Interactions Related to Alzheimers Disease Based on Complex Network
Volume: 17 Issue: 3
Author(s): Jie Yang and Xiong-Fei Jiang
Affiliation:
Keywords: AD associated protein interaction network, signal pathway, conservative interaction pattern
Abstract: A protein domain interaction prediction program was complied using C++ to predict whether a query protein could interact with other hub proteins. It is indicated that the proteins interacting with AATF (Apoptosis-Antagonizing Transcription Factor) possess a common conservative pattern: I-x(0,1)-E-x(2)-[A/E/N/T]-x-[E/K]. Our method is attempted to integrate the characteristics of protein interaction network with the simplest building blocks-conservative patterns.
Export Options
About this article
Cite this article as:
Yang Jie and Jiang Xiong-Fei, A Novel Approach to Predict Protein-Protein Interactions Related to Alzheimers Disease Based on Complex Network, Protein & Peptide Letters 2010; 17 (3) . https://dx.doi.org/10.2174/092986610790780323
DOI https://dx.doi.org/10.2174/092986610790780323 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Challenges in Diagnosing Cerebral Lacunar Infarcts
Current Medical Imaging Proline-Rich Peptides: Multifunctional Bioactive Molecules as New Potential Therapeutic Drugs
Current Protein & Peptide Science Depression, Serotonin and Tryptophan
Current Pharmaceutical Design Biochemical Markers of Cardiovascular Damage from Tobacco Smoke
Current Pharmaceutical Design Biological Activities of Salvia santolinifolia Boiss. A Multifunctional Medicinal Plant
Current Bioactive Compounds Psychiatric/Psychosocial Rehabilitation (PSR) Education: Academic and Professional
Current Psychiatry Reviews Room for Improvement in the Pharmacological Treatment of Anxiety Disorders
Current Pharmaceutical Design Comparison of Two Naloxone Regimens in Opioid-dependent Methadoneoverdosed Patients: A Clinical Trial Study
Current Clinical Pharmacology Molecular Replacement in Cancer Therapy: Reversing Cancer Metabolic and Mitochondrial Dysfunction, Fatigue and the Adverse Effects of Cancer Therapy
Current Cancer Therapy Reviews Editorial[Hot Topic:Membrane Channels as Therapeutic Targets (Executive Editor: Jean-Claude Herve)]
Current Pharmaceutical Design The Crosstalk of RAS with the TGF-β Family During Carcinoma Progression and its Implications for Targeted Cancer Therapy
Current Cancer Drug Targets Plasticity of T Cell Differentiation and Cytokine Signature: A Double-Edged Sword for Immune Responses
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Pharmacological Findings Contribute to the Understanding of the Main Physiological Mechanisms of Memory Retrieval
Current Drug Targets - CNS & Neurological Disorders Stress Echocardiography
Current Pharmaceutical Design Chronic Immune Activation Underlies Morbid Obesity: Is IDO A Key Player?
Current Drug Metabolism Patent Selections
Recent Patents on Inflammation & Allergy Drug Discovery Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease
Mini-Reviews in Medicinal Chemistry Asymmetric Syntheses Based on Organocatalysis
Mini-Reviews in Organic Chemistry Physiological Roles of Neurite Outgrowth Inhibitors in Myelinated Axons of the Central Nervous System – Implications for the Therapeutic Neutralization of Neurite Outgrowth Inhibitors
Current Pharmaceutical Design Impact of Percutaneous Closure of Interatrial Shunts on Migraine Attacks: Single-Operator Series and Review of the Literature
Reviews on Recent Clinical Trials