Isomannide and Derivatives. Chemical and Pharmaceutical Applications

Author(s): E. M.F. Muri, B. A. Abrahim, T. G. Barros, J. S. Williamson, O. A.C. Antunes

Journal Name: Mini-Reviews in Organic Chemistry

Volume 7 , Issue 1 , 2010

Become EABM
Become Reviewer
Call for Editor


Isomannide, 1,4:3,6-dianhydro-D-mannitol, is a commercially available chiral carbohydrate derived from ready dehydration of naturally occurring D-mannitol. This compound and its derivatives have been widely used in many areas such as building blocks for polymers synthesis, pharmaceutically important compounds, catalysts in asymmetric synthesis, chiral auxiliaries, and recently, in the synthesis of ionic liquids. In this review we show examples of these applications of isomannide and derivatives.

Keywords: Isomannide, chiral auxiliaries, catalysts, protease

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2010
Published on: 01 March, 2012
Page: [75 - 83]
Pages: 9
DOI: 10.2174/1570193X11007010075

Article Metrics

PDF: 11