An Overview of Highly Optically Pure Chloramphenicol Bases: Applications and Modifications

Author(s): Kanghui Yang, Hao Fang, Jianzhi Gong, Li Su, Wenfang Xu

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 11 , 2009


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Abstract:

Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.

Keywords: Applications, chloramphenicol bases, structural modifications

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Article Details

VOLUME: 9
ISSUE: 11
Year: 2009
Page: [1329 - 1341]
Pages: 13
DOI: 10.2174/138955709789878097
Price: $65

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