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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

An Overview of Highly Optically Pure Chloramphenicol Bases: Applications and Modifications

Author(s): Kanghui Yang, Hao Fang, Jianzhi Gong, Li Su and Wenfang Xu

Volume 9, Issue 11, 2009

Page: [1329 - 1341] Pages: 13

DOI: 10.2174/138955709789878097

Price: $65

Abstract

Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.

Keywords: Applications, chloramphenicol bases, structural modifications


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