Title: An Overview of Highly Optically Pure Chloramphenicol Bases: Applications and Modifications
VOLUME: 9 ISSUE: 11
Author(s):Kanghui Yang, Hao Fang, Jianzhi Gong, Li Su and Wenfang Xu
Affiliation:Department of Medicinal Chemistry, School of Pharmaceutical Sciences, ShanDong University, 44, West Culture Road, 250012, Ji'nan, ShanDong, P.R. China.
Keywords:Applications, chloramphenicol bases, structural modifications
Abstract: Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.
