Microbubbles as Drug Delivery Systems in Cerebrovascular Diseases

Author(s): Mariacarmela Spinelli, Christian Demitri, Alessandro Sannino, Luca Peruzzotti-Jametti, Marco Bacigaluppi, Giancarlo Comi, Francesco Corea

Journal Name: Recent Patents on Cardiovascular Drug Discovery
Continued as Recent Advances in Cardiovascular Drug Discovery

Volume 4 , Issue 3 , 2009


The field of neurovascular ultrasound is growing rapidly with new applications. While ultrasound contrast agents were initially used to overcome poor transcranial bone windows for identification of cerebral arteries, newgeneration microbubbles in combination with innovative contrast-specific ultrasound techniques now enable potential therapeutic procedures. This article will provide a review of recent and emerging developments along with patents in ultrasound technology and contrast-specific therapeutic techniques for cerebrovascular patients.

Keywords: Ultrasonography, contrast agent, microbubbles, molecular imaging, site-targeted therapy, drug delivery, &, gene therapy

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Article Details

Year: 2009
Page: [222 - 233]
Pages: 12
DOI: 10.2174/157489009789152221
Price: $65

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