Title: Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes
VOLUME: 6 ISSUE: 6
Author(s):Diego Savoia, Andrea Gualandi and Marco Bandini
Affiliation:Dipartimento di Chimica “G. Ciamician”, Universita' di Bologna, via Selmi 2, 40126 Bologna, Italy.
Keywords:Amine, 1,2-diaminocyclohexane, diastereoselectivity, imine, organometallic reagents
Abstract: The double addition of organolithium compounds and allylzinc bromide to the imines prepared from (R,R)-1,2- diaminocyclohexane by condensation with aromatic and heteroaromatic aldehydes gave secondary diamines with high yields and diastereoselectivities apart for the reaction of 2-pyridinealdehyde derivative which occurred with low to moderate stereocontrol.
