Antinociceptive Activity of Lectins from Diocleinae Seeds on Acetic Acid-Induced Writhing Test in Mice

Author(s): Fernanda R. Holanda, Andrelina N. Coelho-de-Sousa, Ana M.S. Assreuy, Jose Henrique Leal-Cardoso, Alana F. Pires, Kyria S. do Nascimento, Cicero S. Teixeira, Benildo S. Cavada, Claudia F. Santos

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 9 , 2009

Become EABM
Become Reviewer
Call for Editor


Diocleinae lectins administered per oral route in mice inhibited the abdominal constrictions induced by acetic acid. The percentage of the lectins antinociception varied from 61% for Canavalia grandiflora (ConGf) to 20% for Dioclea violacea. ConGf inhibited contortions at all doses tested but not in a dose-dependent manner, involving carbohydrate recognition.

Keywords: Lectins, Diocleinae subtribe, antinociception, Canavalia grandiflora, carbohydrate recognition

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2009
Page: [1088 - 1092]
Pages: 5
DOI: 10.2174/092986609789055304
Price: $65

Article Metrics

PDF: 10