Identification and Characterization of a Novel Oligomeric Decaprenyl Diphosphate Synthase

Author(s): Hyeong H. Choe, Heejin Hwang, Seung Bum Kim, Sangyoung Yoon, Do Hyun Jo, Yeonwoo Ryu, T. Doohun Kim

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 9 , 2009


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Abstract:

A novel oligomeric decaprenyl pyrophosphate synthase was identified. Circular dichroism measurements indicated that it is alpha-helical, and stable against pH changes and denaturants. Three peptides corresponding to the conserved regions were synthesized and metal affinities were investigated. Crystallographic analyses of this oligomeric DDS are currently in progress.

Keywords: Decaprenyl diphosphate synthase, circular dichroism, metal affinities

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Article Details

VOLUME: 16
ISSUE: 9
Year: 2009
Page: [1036 - 1040]
Pages: 5
DOI: 10.2174/092986609789055359
Price: $65

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