Bioinformatics Comparison of G Protein of Isfahan Virus with the Same Proteins of Two Other Closely Related Viruses of the Genus Vesiculovirus

Author(s): Hassan Mohabatkar, Sasan Mohsenzadeh

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 9 , 2009


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Abstract:

Since there are not much experimental data available about different structural properties of Isfahan virus (ISFV), in the present investigation, computational study of G protein of ISFV was performed and the results were compared with G proteins of Chandipura virus (CHPV) and Piry virus (PV). Calculation of amino acid compositions of G proteins of viruses was done by PseAAC server. Predictions of localization, sequence of signal peptides, C, N and O glycosylation sites, transmembrane helices, cysteine bond positions and B cell epitopes of G proteins were performed by Virus- PLoc, Signal-CF, EnsembleGly, MemBrain, DiANNA and BCPREDS servers respectively. Similarities and differences between these glycoproteins were predicted and discussed.

Keywords: Isfahan virus, Chandipura virus, Piry virus, Bioinformatics

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Article Details

VOLUME: 16
ISSUE: 9
Year: 2009
Page: [1017 - 1023]
Pages: 7
DOI: 10.2174/092986609789055269
Price: $65

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