Title: Tityus serrulatus Scorpion Venom and Toxins: An Overview
VOLUME: 16 ISSUE: 8
Author(s):Camila T. Cologna, Silvana Marcussi, Jose R. Giglio, Andreimar M. Soares and Eliane C. Arantes
Affiliation:Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, USP., Departamento de Fisica e Quimica, Av. do Cafe, s/n, 14040-903, Ribeirao Preto-SP, Brazil.
Keywords:Scorpion, Tityus serrulatus venom, neurotoxins, ion channels, hyaluronidase, proteases, peptides
Abstract: Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), its long-chain Na+-channel toxins (NaTx), which include α- and β-neurotoxins, short-chain K+-channel toxins (KTx), hyaluronidase, proteases and other peptides hitherto identified.
