Tityus serrulatus Scorpion Venom and Toxins: An Overview

Author(s): Camila T. Cologna, Silvana Marcussi, Jose R. Giglio, Andreimar M. Soares, Eliane C. Arantes

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 8 , 2009

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Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), its long-chain Na+-channel toxins (NaTx), which include α- and β-neurotoxins, short-chain K+-channel toxins (KTx), hyaluronidase, proteases and other peptides hitherto identified.

Keywords: Scorpion, Tityus serrulatus venom, neurotoxins, ion channels, hyaluronidase, proteases, peptides

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Article Details

Year: 2009
Page: [920 - 932]
Pages: 13
DOI: 10.2174/092986609788923329
Price: $65

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PDF: 149