Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins

Author(s): Sandro G. Soares, Leandro L. Oliveira

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 8 , 2009


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Abstract:

Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.

Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease

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Article Details

VOLUME: 16
ISSUE: 8
Year: 2009
Published on: 01 March, 2012
Page: [913 - 919]
Pages: 7
DOI: 10.2174/092986609788923293
Price: $65

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