Involvement of MAPK Signalling in Human Villous Trophoblast Differentiation

Author(s): C. Vaillancourt, D. Lanoix, F. Le Bellego, G. Daoud, J. Lafond

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 8 , 2009

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Human villous trophoblast differentiation is a complex and highly regulated process essential for the well-being of the pregnancy and fetal development. In this review, we present an overview of the role of MAPKs signalling in morphological and functional differentiation of villous trophoblast.

Keywords: Human placenta, villous cytotrophoblast, differentiation, mitogen-activated protein kinases, cell signalling, syncytiotrophoblast, peroxisome proliferator-activated receptors, Src family kinase, drug

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Article Details

Year: 2009
Page: [962 - 973]
Pages: 12
DOI: 10.2174/138955709788681663
Price: $65

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