Structural and Functional Diversity Among Eukaryotic Hsp70 Nucleotide Exchange Factors

Author(s): Mehdi Kabani

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 6 , 2009

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Since their recent identification, eukaryotic Hsp70 nucleotide exchange factors (NEFs) have gained increasing interest due to their engagement in vital cellular processes. Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human diseases such as cystic fibrosis or amyloidoses.

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Article Details

Year: 2009
Page: [623 - 630]
Pages: 8
DOI: 10.2174/092986609788490186
Price: $65

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