Title: Memory-Enhancing Drugs: A Molecular Perspective
VOLUME: 9 ISSUE: 7
Author(s):Barbara Monti and Antonio Contestabile
Affiliation:Deptment of Biology, University of Bologna, Via Selmi 3, 40126, Bologna, Italy.
Keywords:Memory, neurodegenerative disease, acetylcholine, AMPA receptor, CREB, chromatin
Abstract: Neurodegenerative diseases associated with dementia are characterized by cognitive deficits and memory impairment, thus stimulating research for memory enhancing drugs. We survey here the state of the art of research and clinical trials on these drugs from cholinesterase inhibitors and drugs acting on neurotransmitter receptors to drugs acting on gene expression.
