The Concept of a Green Drug, Curcumin and It ’ s Derivatives as a Model System

Author(s): K. S. Raja, R. Balambika, S. Dolai, W. Shi

Journal Name: Mini-Reviews in Organic Chemistry

Volume 6 , Issue 2 , 2009


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Abstract:

Only 5-15% of the ∼25000 existing species of plants have been examined for the presence of biologically active compounds. The ancient medical systems use a much larger palette of herbs for therapy. Systematic drug discovery involving using cues provided from traditional medical systems is bound to produce a new generation of green drugs. Curcumin the primary active ingredient in Curcuma longa is used as a model to enunciate the concept of green drug development. Synthetic and formulation based approaches to optimize the bioactivity of curcumin is presented.

Keywords: Green drug, curcumin, traditional medicine, GRAS, renewable resource, derivative

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Article Details

VOLUME: 6
ISSUE: 2
Year: 2009
Page: [152 - 158]
Pages: 7
DOI: 10.2174/157019309788167684
Price: $65

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