Implication of Aberrant Glycosylation in Cancer and Use of Lectin for Cancer Biomarker Discovery

Author(s): Yong-Sam Kim, Hyang Sook Yoo, Jeong Heon Ko

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 5 , 2009

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Abstract:

Aberrant glycosylation is frequently found in cancer, and efforts for biomarker discovery include the preparation of aberrant glycoproteins as promising analytes. Several lectins that bind to aberrant glycans and can be thus used to capture and enrich aberrant glycoproteins in the frontal stage during biomarker discovery are to be introduced.

Keywords: Aberrant glycosylation, biomarker, cancer, lectin, glycosyltransferase

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Article Details

VOLUME: 16
ISSUE: 5
Year: 2009
Page: [499 - 507]
Pages: 9
DOI: 10.2174/092986609788167798
Price: $65

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