SELDI Protein Chip Technology for the Detection of Serum Biomarkers for Liver Disease

Author(s): Lei Chen, Sarwat Fatima, Jirun Peng, Xisheng Leng

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 5 , 2009

Become EABM
Become Reviewer

Abstract:

The need to identify disease biomarkers is critical to ensure fast diagnosis and timely treatment. Surface enhanced laser desorption/ionization time-of-fight mass spectrometry (SELDI-TOF-MS) is a widely used technology platform for diagnostic biomarker discovery. This short review provides an overview of how it functions and also describes its advantages and drawbacks.

Keywords: Surface enhanced laser desorption/ionization, proteomics, biomarker, liver diseases

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 16
ISSUE: 5
Year: 2009
Page: [467 - 472]
Pages: 6
DOI: 10.2174/092986609788167851
Price: $65

Article Metrics

PDF: 6