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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

SELDI Protein Chip Technology for the Detection of Serum Biomarkers for Liver Disease

Author(s): Lei Chen, Sarwat Fatima, Jirun Peng and Xisheng Leng

Volume 16, Issue 5, 2009

Page: [467 - 472] Pages: 6

DOI: 10.2174/092986609788167851

Price: $65

Abstract

The need to identify disease biomarkers is critical to ensure fast diagnosis and timely treatment. Surface enhanced laser desorption/ionization time-of-fight mass spectrometry (SELDI-TOF-MS) is a widely used technology platform for diagnostic biomarker discovery. This short review provides an overview of how it functions and also describes its advantages and drawbacks.

Keywords: Surface enhanced laser desorption/ionization, proteomics, biomarker, liver diseases


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