Title: Medicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs
VOLUME: 9 ISSUE: 5
Author(s):Esra Koc and S. Guniz Kucukguzel
Affiliation:Marmara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 34668, Turkey.
Keywords:Nitric oxide, NO-NSAID, anti-inflammatory
Abstract: Nitric Oxide, which acts as a non-specific cytotoxic mediator and a biological messenger on immunological competence, has been gaining significantly increasing importance. As an alternative to conventional NSAIDs having significant side effects, pharmacologically improved and therapeutically enhanced NO releasing non-steroidal antiinflammatory drugs with less side effects are being planned to produce.
