Medicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs

Author(s): Esra Koc, S. Guniz Kucukguzel

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 5 , 2009

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Nitric Oxide, which acts as a non-specific cytotoxic mediator and a biological messenger on immunological competence, has been gaining significantly increasing importance. As an alternative to conventional NSAIDs having significant side effects, pharmacologically improved and therapeutically enhanced NO releasing non-steroidal antiinflammatory drugs with less side effects are being planned to produce.

Keywords: Nitric oxide, NO-NSAID, anti-inflammatory

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Article Details

Year: 2009
Page: [611 - 619]
Pages: 9
DOI: 10.2174/138955709788167556
Price: $65

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