Abstract
We report a case with severe persistent pulmonary hypertension (PPHN) associated with congenital cystic adenomatoid malformation of the lung (CCAM) treated with sildenafil PO. The case was unresponsive to the High-Frequency Oscillatory Ventilation (HFOV), with a oxygenation index (OI) of 50 before sildenafil. Substantial improvement in OI was followed by extubation and survival. No side-effects were noted.
Keywords: PPHN, CCAM, sildenafil, HFOV, oxygenation index
Current Pediatric Reviews
Title: Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report
Volume: 5 Issue: 2
Author(s): Gianfranco Maffei, Vincenzo Manuppelli and Rosario Magaldi
Affiliation:
Keywords: PPHN, CCAM, sildenafil, HFOV, oxygenation index
Abstract: We report a case with severe persistent pulmonary hypertension (PPHN) associated with congenital cystic adenomatoid malformation of the lung (CCAM) treated with sildenafil PO. The case was unresponsive to the High-Frequency Oscillatory Ventilation (HFOV), with a oxygenation index (OI) of 50 before sildenafil. Substantial improvement in OI was followed by extubation and survival. No side-effects were noted.
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Cite this article as:
Maffei Gianfranco, Manuppelli Vincenzo and Magaldi Rosario, Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report, Current Pediatric Reviews 2009; 5 (2) . https://dx.doi.org/10.2174/157339609788185767
DOI https://dx.doi.org/10.2174/157339609788185767 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
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