Abstract
Environmental tobacco smoke (ETS) exposure has been associated with adverse health outcomes in all stages of life. Embryogenesis is a particularly important period to study because exposures during this period can alter proper growth and development of all organs. ETS exposure to the developing fetus has been associated with low birth weight infants, premature births and sudden infant death syndrome. In addition, prenatal ETS exposure has been identified as a significant risk factor for the development of asthma in a number of epidemiologic studies. This review surveys the current literature available linking in utero ETS with the development of asthma, explores the role of nicotine as a possible causative agent involved in the pathogenesis of these findings, and examines the literature linking in utero ETS exposure with broader effects on airway physiology and response.
Keywords: Tobacco smoke, nicotine, nicotinic acetylcholine receptors, asthma, lung development
Current Respiratory Medicine Reviews
Title: Tobacco Smoke Exposure, Nicotine, and the Embryologic Origins of Asthma
Volume: 5 Issue: 2
Author(s): Cherry Wongtrakool and Jesse Roman
Affiliation:
Keywords: Tobacco smoke, nicotine, nicotinic acetylcholine receptors, asthma, lung development
Abstract: Environmental tobacco smoke (ETS) exposure has been associated with adverse health outcomes in all stages of life. Embryogenesis is a particularly important period to study because exposures during this period can alter proper growth and development of all organs. ETS exposure to the developing fetus has been associated with low birth weight infants, premature births and sudden infant death syndrome. In addition, prenatal ETS exposure has been identified as a significant risk factor for the development of asthma in a number of epidemiologic studies. This review surveys the current literature available linking in utero ETS with the development of asthma, explores the role of nicotine as a possible causative agent involved in the pathogenesis of these findings, and examines the literature linking in utero ETS exposure with broader effects on airway physiology and response.
Export Options
About this article
Cite this article as:
Wongtrakool Cherry and Roman Jesse, Tobacco Smoke Exposure, Nicotine, and the Embryologic Origins of Asthma, Current Respiratory Medicine Reviews 2009; 5 (2) . https://dx.doi.org/10.2174/157339809788189996
DOI https://dx.doi.org/10.2174/157339809788189996 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Subject Index to Volume 2
Current Pharmacogenomics Pharmacokinetic and Toxicological Characteristics of Tripterigium Glycosides and Their Derivatives
Current Drug Metabolism Sulfated Oligosaccharides: New Targets for Drug Development?
Current Medicinal Chemistry A Timely Review of State-of-the-Art Chronopharmaceuticals Synchronized with Biological Rhythms
Current Drug Delivery Toll-Like Receptors, Cytokines and the Immunotherapeutics of Asthma
Current Pharmaceutical Design IgE-Binding Epitope Analysis of Bla g 5, the German Cockroach Allergen
Protein & Peptide Letters Recent Approaches on Novel Topical Delivery Systems for Atopic Dermatitis Treatment
Recent Patents on Drug Delivery & Formulation Targeted Drugs and Nanomedicine: Present and Future
Current Pharmaceutical Design Lactobacillus Rhamnosus Cell Lysate in the Management of Resistant Childhood Atopic Eczema
Inflammation & Allergy - Drug Targets (Discontinued) Receptor-based 3D-QSAR in Drug Design: Methods and Applications in Kinase Studies
Current Topics in Medicinal Chemistry Cellular and Molecular Effects of Macrolides on Leukocyte Function
Current Pharmaceutical Design Airway Remodeling: Effect of Current and Future Asthma Therapies
Current Respiratory Medicine Reviews Does Phosphodiesterase 11A (PDE11A) Hold Promise as a Future Therapeutic Target?
Current Pharmaceutical Design Active Metabolites Resulting from Decarboxylation, Reduction and Ester Hydrolysis of Parent Drugs
Current Drug Metabolism Paracetamol-Induced Fixed Drug Eruption at an Unusual Site
Recent Patents on Inflammation & Allergy Drug Discovery Adipose-Derived Stromal/Stem Cells (ASC) in Regenerative Medicine: Pharmaceutical Applications
Current Pharmaceutical Design Strategies for Efficient Lead Structure Discovery from Natural Products
Current Medicinal Chemistry Anti-Inflammatory Activities of α2-Agonists
Current Drug Targets - Inflammation & Allergy Bioactive N-Phenylimidazole Derivatives
Current Chemical Biology Utility of Anti-Arrhythmic Medications in ‘Lone Atrial Fibrillation’
Current Pharmaceutical Design