Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

Author(s): Zhenzhen Wen, Yonghua Wang, Xun Xu, Bo Yang, Wencheng Li, Mingquan Xie

Journal Name: Protein & Peptide Letters

Volume 17 , Issue 6 , 2010

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SsHSP14.1, a novel sHSP from the hyper-thermophilic archaeon Sulfolobus solfataricus (S. solfataricus), is reported herein to function to protect EcoR I from heat-induced inactivation. A predicted salt bridge and hydrophobic interactions were found to be important for this function.

Keywords: Small heat shock proteins (sHSPs), SsHSP14.1, Sulfolobus solfataricus (S. solfataricus), EcoR I, salt bridge, oligomer

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Article Details

Year: 2010
Page: [751 - 758]
Pages: 8
DOI: 10.2174/092986610791190273
Price: $65

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