Concise Synthesis of Non-Protein Amino Acid from Natural Product via Schmidt Reaction

Author(s): Kamila Gajcy, Tadeusz Librowski, Stanislaw Lochynski

Journal Name: Letters in Organic Chemistry

Volume 6 , Issue 3 , 2009

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Abstract:

In this work we aimed at finding a concise method for the design of the new pharmacologically active compound 6, which is a precursor to obtaining non-protein amino acid 7 considered as GABA analogue, furthermore it can be used to construct enantiopure, conformationally restricted peptides. For this purpose the Schmidt reaction was applied.

Keywords: Amino acids, schmidt reaction, natural products, terpenoids

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Article Details

VOLUME: 6
ISSUE: 3
Year: 2009
Page: [186 - 188]
Pages: 3
DOI: 10.2174/157017809787893037
Price: $65

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