Transport Properties of Cartilaginous Tissues

Author(s): Alicia R. Jackson, Wei Yong Gu

Journal Name: Current Rheumatology Reviews

Volume 5 , Issue 1 , 2009


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Abstract:

Cartilaginous tissues, such as articular cartilage and intervertebral disc, are avascular tissues, which rely on transport for cellular nutrition. Comprehensive knowledge of transport properties in such tissues is therefore necessary in the understanding of nutritional supply to cells. Furthermore, poor cellular nutrition in cartilaginous tissues is believed to be a primary source of tissue degeneration, which may result in osteoarthritis (OA) or disc degeneration. In this minireview, we present an overview of the current status of the study of transport properties and behavior in cartilaginous tissues. The mechanisms of transport in these tissues, as well as experimental approaches to measuring transport properties and results obtained are discussed. The current status of bioreactors used in cartilage tissue engineering is also presented.

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Article Details

VOLUME: 5
ISSUE: 1
Year: 2009
Page: [40 - 50]
Pages: 11
DOI: 10.2174/157339709787315320
Price: $65

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PDF: 46