Title: Resurrecting Clinical Pharmacology As a Context for Alzheimer Disease Drug Development
VOLUME: 6 ISSUE: 1
Author(s):Robert E. Becker, Latha K. Unni and Nigel H. Greig
Affiliation:P.O. Box 442, South Freeport, ME, USA.
Keywords:Clinical Pharmacology, Alzheimer Disease, Drug Development, acetylcholinesterase (AChE) inhibition, cytoplasmic AChE
Abstract: Commercial priorities have been identified as negative factors in drug development. We trace the problem to inattention to sound clinical pharmacology practices. When properly applied, clinical pharmacology and associated drug development sciences can, hand in hand, facilitate success in commercial drug development.