Rapid Synthesis of Taxifolione and Taxifolial D, Two Metabolites from the Marine Alga Caulerpa taxifolia

Author(s): Fabien Fecourt, Cedric Carlier, Patrick Pale.

Journal Name: Letters in Organic Chemistry

Volume 6 , Issue 1 , 2009

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Abstract:

The synthesis of two natural products - Taxifolione and Taxifolial D – isolated from the marine alga Caulerpa taxifolia invading the Mediterranean Sea was performed. Coupling reactions allowed for a rapid synthesis. The surprising Z configuration of Taxifolial D was confirmed after synthesis and comparison of each synthetic stereoisomer.

Keywords: Terpenoids, enynes, cross-coupling, antitumor agents

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Article Details

VOLUME: 6
ISSUE: 1
Year: 2009
Page: [65 - 70]
Pages: 6
DOI: 10.2174/157017809787003179

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