Helicobacter Pylori, Zinc and Iron in Oxidative Stress-Induced Injury of Gastric Mucosa

Author(s): J. Dovhanj, K. Kljaic, K. Dodig-Curkovic, M. Curkovic, M. Volarevic, K. Marjanovic

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 1 , 2009

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A number of study have suggested a relationship between Helicobacter pylori infection and oxidative stress in the gastric epithelium. The oxidant- induced changes in zinc, iron, and vitamin C increase susceptibility to oxidative injury. Understanding of pathophysiologic mechanisms may provide new therapeutic strategies in treatment of oxidative injury of mucosa.

Keywords: Helicobacter pylori, zinc, iron, vitamin C, oxidative stress

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Article Details

Year: 2009
Page: [26 - 30]
Pages: 5
DOI: 10.2174/138955709787001767

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PDF: 17