Role of Nitric Oxide in Physiology and Pathology of the Gastrointestinal Tract

Author(s): A. Stanek, A. Gadowska-Cicha, K. Gawron, T. Wielkoszynski, B. Adamek, G. Cieslar, A. Wiczkowski, A. Sieron

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 14 , 2008

Become EABM
Become Reviewer
Call for Editor


In this paper the physiological role of NO and isoforms of NOS in the gastrointestinal tract and the involvement of NO in pathological processes of digestive tract as well as the perspective of therapeutic use of NO-donating drugs and selective inhibitors of phosphodiesterase in the treatment of gastric diseases were presented.

Keywords: Nitric oxide, constitutive nitric oxide synthase, inducible nitric oxide synthase, gastrointestinal tract, inflammatory process, malignant transformations, NO-donor drugs, phosphodiesterase inhibitors

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2008
Published on: 01 March, 2012
Page: [1549 - 1560]
Pages: 12
DOI: 10.2174/138955708786786462
Price: $65

Article Metrics

PDF: 6