Abstract
The role played by synthetic organic chemistry of marine metabolites as potential leads for drug discovery of antimalarial agents is discussed. Syntheses of the most promising molecules are summarized, with emphasis on structureactivity relationship (SAR) studies and their mechanism of action.
Keywords: Natural products, marine metabolites, drug discovery, synthesis, retrosynthetic analysis, antiprotozoal, antimalarial, antiplasmodial
Mini-Reviews in Medicinal Chemistry
Title: Synthesis of Marine Natural Products with Antimalarial Activity
Volume: 8 Issue: 12
Author(s): Ines Mancini, Graziano Guella and Andrea Defant
Affiliation:
Keywords: Natural products, marine metabolites, drug discovery, synthesis, retrosynthetic analysis, antiprotozoal, antimalarial, antiplasmodial
Abstract: The role played by synthetic organic chemistry of marine metabolites as potential leads for drug discovery of antimalarial agents is discussed. Syntheses of the most promising molecules are summarized, with emphasis on structureactivity relationship (SAR) studies and their mechanism of action.
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Cite this article as:
Mancini Ines, Guella Graziano and Defant Andrea, Synthesis of Marine Natural Products with Antimalarial Activity, Mini-Reviews in Medicinal Chemistry 2008; 8 (12) . https://dx.doi.org/10.2174/138955708786141007
DOI https://dx.doi.org/10.2174/138955708786141007 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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