A Technological Update of Molecular Diagnostics for Infectious Diseases

Author(s): Yu-Tsueng Liu

Journal Name: Infectious Disorders - Drug Targets
(Formerly Current Drug Targets - Infectious Disorders)

Volume 8 , Issue 3 , 2008

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Abstract:

Identification of a causative pathogen is essential for the choice of treatment for most infectious diseases. Many FDA approved molecular assays; usually more sensitive and specific compared to traditional tests, have been developed in the last decade. A new trend of high throughput and multiplexing assays are emerging thanks to technological developments for the human genome sequencing project. The applications of microarray and ultra high throughput sequencing technologies for diagnostic microbiology are reviewed. The race for the $1000 genome technology by 2014 will have a profound impact in diagnosis and treatment of infectious diseases in the near future.

Keywords: Diagnostic microbiology, microarray, next-generation sequencing

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Article Details

VOLUME: 8
ISSUE: 3
Year: 2008
Page: [183 - 188]
Pages: 6
DOI: 10.2174/1871526510808030183
Price: $65

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