Title: Differential Expression of Genes in Obesity and Type 2 Diabetes Mellitus
VOLUME: 4 ISSUE: 3
Author(s):Allam Appa Rao
Affiliation:Department of Computer Science and Systems Engineering, Andhra University, Visakhapatnam- 530003, India.
Keywords:obesity, type 2 diabetes mellitus, metabolism, cytokine-cytokine receptor interaction, immune system pathways, inflammatory pathway, Carbon reactive protein (CRP)
Abstract: Both obesity and type 2 diabetes mellitus are common. In a gene expression profile study, it was noted that genes concerned with carbohydrate, lipid and amino acid metabolism, and signal transduction pathways are upregulated, while genes involved in cell adhesion, cytokine-cytokine receptor interaction, insulin signaling, immune system pathways, and inflammatory pathway are differentially expressed both in obesity and type 2 diabetes.
