Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review

Author(s): Sara Mazzucco, Andrea Cipriani, Corrado Barbui, Salvatore Monaco

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 8 , 2008

Become EABM
Become Reviewer
Call for Editor


Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and nonrandomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.

Keywords: Neuroleptics, typical antipsychotics, atypical antipsychotics, dopamine, dementia, cerebrovascular events

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2008
Page: [776 - 783]
Pages: 8
DOI: 10.2174/138955708784912175
Price: $65

Article Metrics

PDF: 16