Pharmacological Strategies for Neuroprotection in Traumatic Brain Injury

Author(s): J. S. Jennings, A. M. Gerber, M. L. Vallano

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 7 , 2008

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Traumatic brain injury affects over a million Americans annually, but pharmacological therapy remains limited. Current standards of care in acute, subacute and chronic phases of injury are primarily supportive. This review discusses pharmacological strategies and future directions in patient treatment emphasizing pleiotropic agents targeting inflammation, oxidative damage, and glutamate excitotoxicity.

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Article Details

Year: 2008
Published on: 01 March, 2012
Page: [689 - 701]
Pages: 13
DOI: 10.2174/138955708784567377
Price: $65

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