Chemokines as Pharmacological Targets

Author(s): Emanuela Galliera, Massimiliano M. Corsi, Raffaella Bonecchi, Massimo Locati, Alberto Mantovani

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 7 , 2008

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Abstract:

Chemokines play a key role in immune processes by controlling leukocyte recruitment in physiological and pathological condition. This review discusses the regulation of the chemokine system, its role in human diseases, and its potential relevance as a new pharmacological target.

Keywords: Chemokine, chemokine receptors, inflammation, GPCR inhibitors

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Article Details

VOLUME: 8
ISSUE: 7
Year: 2008
Page: [638 - 646]
Pages: 9
DOI: 10.2174/138955708784567386
Price: $65

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