Protein Domain Annotation with Predicted Domain-Domain Interaction Networks

Author(s): Xing-Ming Zhao, Yong Wang, Luonan Chen, Kazuyuki Aihara

Journal Name: Protein & Peptide Letters

Volume 15 , Issue 5 , 2008


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Abstract:

This paper presents a framework for annotating protein domains with predicted domain-domain interaction networks. Specially, domain annotation is formalized as a multi-class classification problem in this work. The numerical experiments on InterPro domains show promising results, which proves the efficiency of our proposed methods.

Keywords: Predicted domain-domain interaction, domain annotation, majority rule, diffusion kernel, shortest path

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Article Details

VOLUME: 15
ISSUE: 5
Year: 2008
Page: [456 - 462]
Pages: 7
DOI: 10.2174/092986608784567609
Price: $65

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