Title: Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease
VOLUME: 8 ISSUE: 5
Author(s):S. Bastianetto, S. Krantic and R. Quirion
Affiliation:Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Verdun, Quebec, Canada H4H 1R3.
Keywords:Alzheimer's disease, polyphenols, neuroprotection
Abstract: Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimers disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.
