A Novel Four Component One-Pot Access to 4,6-diaryl-2-Pyridinone and 4-aryl-5,6,7,8-tetrahydro-2-quinolinones

Title: A Novel Four Component One-Pot Access to 4,6-diaryl-2-Pyridinone and 4-aryl-5,6,7,8-tetrahydro-2-quinolinones

Volume: 5 Issue: 4

Author(s): Chao-Guo Yan, Xi-Mei Cai, Qi-Fang Wang and Jing Sun

Affiliation:

Keywords: Pyridine, pyridone, quinolinone, microwave irradiation, multi-component reaction, cyclocondensation

Abstract: An efficient one-pot procedure was developed for the synthesis of 4,6-diaryl-2-pyridinones and 4-aryl-8- arylidene-5,6,7,8-tetrahydro-2- quinolinones based on cyclocondensation reactions of N-ethoxycarbonylmethylpyridinium chloride or N-carbamoylmethyl pyridinium chloride with aromatic aldehydes and substituted acetophenones or cyclohexanone. The multi-component reaction is performed by microwave irradiation with the reaction substances in the system of NH4OAc/HOAc.

Cite this article as:

Yan Chao-Guo, Cai Xi-Mei, Wang Qi-Fang and Sun Jing, A Novel Four Component One-Pot Access to 4,6-diaryl-2-Pyridinone and 4-aryl-5,6,7,8-tetrahydro-2-quinolinones, Letters in Organic Chemistry 2008; 5 (4) . https://dx.doi.org/10.2174/157017808784049425