Abstract
Abdominal aortic surgery is relatively common associated with considerable postoperative morbidity and mortality. The aortic cross-clamping for the implantation of a vascular prosthetic graft induces a systemic inflammatory response (SIR) because of an ischemia-reperfusion (IR) injury. In our experimental models we have reported that propofol anesthesia, compared with sevoflurane, after IR modulates SIR and this effect might result in renal protection.
Keywords: Propofol, Systemic inflammatory response, Aortic surgery, Aortic cross-clamping
Letters in Drug Design & Discovery
Title: Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery
Volume: 5 Issue: 2
Author(s): Jose M. Rodriguez-Lopez and Francisco S. Lozano
Affiliation:
Keywords: Propofol, Systemic inflammatory response, Aortic surgery, Aortic cross-clamping
Abstract: Abdominal aortic surgery is relatively common associated with considerable postoperative morbidity and mortality. The aortic cross-clamping for the implantation of a vascular prosthetic graft induces a systemic inflammatory response (SIR) because of an ischemia-reperfusion (IR) injury. In our experimental models we have reported that propofol anesthesia, compared with sevoflurane, after IR modulates SIR and this effect might result in renal protection.
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Cite this article as:
Rodriguez-Lopez M. Jose and Lozano S. Francisco, Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery, Letters in Drug Design & Discovery 2008; 5 (2) . https://dx.doi.org/10.2174/157018008783928490
DOI https://dx.doi.org/10.2174/157018008783928490 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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