Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery

Author(s): Jose M. Rodriguez-Lopez, Francisco S. Lozano

Journal Name: Letters in Drug Design & Discovery

Volume 5 , Issue 2 , 2008

Become EABM
Become Reviewer


Abdominal aortic surgery is relatively common associated with considerable postoperative morbidity and mortality. The aortic cross-clamping for the implantation of a vascular prosthetic graft induces a systemic inflammatory response (SIR) because of an ischemia-reperfusion (IR) injury. In our experimental models we have reported that propofol anesthesia, compared with sevoflurane, after IR modulates SIR and this effect might result in renal protection.

Keywords: Propofol, Systemic inflammatory response, Aortic surgery, Aortic cross-clamping

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2008
Page: [148 - 151]
Pages: 4
DOI: 10.2174/157018008783928490
Price: $65

Article Metrics

PDF: 2